An early morning fire in a Hilo home injured two people and destroyed the structure. The fire was reported at 4:14 a.m. Monday on Uhaloa Road. When firefighters arrived, the front bedroom of the home was engulfed in flames. They brought the fire under control at 4:35 a.m. Two people were taken to Hilo Medical Center with injuries caused by the fire. A damage estimate is not yet available and the cause of the fire is under investigation.